Tuesday, November 6, 2007

Anti-Cancer agents ?



Bryozoans have been under investigation for being a potential anti-cancer and antineoplastic agents (antitumer antibiotics). Bugula neritina (above image) from the class Gymnolaemata (O. Cheilostomata) in particular has been under investigation.

Bryostatin are being extracted and tested as a potential potent antineoplastic agent. They have been reported to stimulate normal human hematopoietic cells (stem cells that give rise to all blood cell types) by directly stimulating bone marrow progenitor cells to form colonies (in vitro tests), and they functionally activate neutrophils.

Further reading, or interest in an article that tests Bryostatin can be found in Annotated Bibliography section.

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